Preliminary Program

Go directly to a day's program:
Wednesday | Thursday | Friday | Saturday

All General Sessions to be held in Mediterranean East and Center

Tuesday, January 15

5:00-7:00pm

Early Registration
Mediterranean Center Foyer. Main Lobby Level.


Wednesday, January 16 [back to top of page]

7:30-9:00

Registration/Continental Breakfast
Mediterranean Center & Grande Promenade Foyers. Main Lobby Level.

9:00-9:10 Welcome & Explanation of sessions
William J. Steinbach, MD
9:10-9:50 Keynote Interdisciplinary Lecture: Clinical aspergillosis for basic scientists
David A. Stevens, MD
9:50-10:30 Keynote Interdisciplinary Lecture: How can molecular biology help us understand Aspergillus and aspergillosis
Aspergillus molecular biology for clinicians

Joan W. Bennett, PhD

10:30-10:55

BREAK
Grande Promenade 

Molecular Diagnostics
10:55-11:00 Session Introduction
Moderators: Dennis M. Dixon, PhD and Paul E. Verweij, MD PhD
11:00-11:25 DNA v. RNA amplification-detection platforms
David S. Perlin, PhD
11:25-11:50 Proteome analysis for pathogenicity and new diagnostic markers
Olaf Kniemeyer, PhD
11:50-12:15 Aspergillus PCR: Formidable challenges and progress
Lena Klingspor, MD PhD
12:15-12:40 Conventional or molecular measurement of Aspergillus load
Karl V. Clemons, PhD

12:40-2:15

LUNCH
Grande Promenade 

Pathogenesis and Clinical Manifestations in Different Hosts
2:15-2:20 Session Introduction
Moderators: Scott G. Filler, MD and George A. Sarosi, MD
2:20-2:45 Invasive aspergillosis in chronic granulomatous disease
Brahm H. Segal, MD
2:45-3:10 Difference in invasive aspergillosis in solid organ transplant recipients
Shahid Husain, MD
3:10-3:35 Invasive disease in patients with leukemia
Johan Maertens, MD
3:35-4:00 Invasive aspergillosis in steroid-treated patients
Dimitrios P. Kontoyannis, MD

4:00-4:25

BREAK
Grande Promenade 

Neutrophils and Aspergillus
4:25-4:30 Session Introduction
Moderators: Brahm H. Segal, MD and Michael Kleinberg, MD PhD
4:30-4:55 Neutrophils and damage during invasive aspergillosis
Steve M. Holland, MD
4:55-5:20 Granulocyte products as alarmins to enhance innate and adaptive immunity
De Yang, PhD
5:20-5:45 Neutrophil contribution to defense against invasive aspergillosis
Tobias Hohl, MD, PhD

5:45-7:15

WELCOME RECEPTION
Ocean Room -  Pool Area. Lower Lobby Level.

Satellite Symposia
Evaluation of Echinocandins for the Treatment of Invasive Aspergillosis
Starlight Ballroom – Top of Resort
7:30-9:30 Moderator: William J. Steinbach, MD

Echinocandin activity against Aspergillus and importance of pharmacodynamic optimization
James S. Lewis, PharmD

Azole resistance
Paul E. Verweij, MD PhD

Paradoxical echinocandin activity: a limited in vitro phenomenon?
Nathan P. Weiderhold, PharmD


Thursday, January 17 [back to top of page]

7:30-8:45

BREAKFAST
Grande Promenade 

8:00-8:45 Meet the Professors (parallel sessions)

Illuminating cases for the thinking physician
George A. Sarosi, MD, John E. Bennett, MD and Laurence F. Mirels, MD
Mediterranean East and Center

Sexual structures in Aspergillus - morphology, importance, and genomics
David M. Geiser, PhD
Regency Ballroom

Utilizing the Aspergillus Cell Wall
Mediterranean East and Center
8:55-9:00 Session Introduction
Moderators: David S. Perlin, PhD and Jennifer Nielsen Kahn, PhD
9:00-9:25 Galactomannan: more than one molecule
Jean-Paul Latgé, PhD
9:25-9:50 Chitin synthases of aspergilli: Functions in tip growth and morphogenesis in Aspergillus nidulans
Hiroyuki Horiuchi, PhD
9:50-10:15 Glucan diagnosis for invasive aspergillosis
Francisco M. Marty, MD

10:15-10:40

BREAK
Grande Promenade 

Aspergillus Sinusitis
10:40-10:45 Session Introduction
Moderators: John E. Bennett, MD and Kent Sepkowitz, MD
10:45-11:10 Controversies surrounding categorization of fungal sinusitis
Arunaloke Chakrabarti, MD
11:10-11:35 Management  of invasive Aspergillus sinusitis
Richard D. deShazo, MD
11:35-12:05 Aspergillus sinusitis in animals and parallels in human disease
Michael J. Day, PhD
12:05-12:30 Allergic Fungal Sinusitis
Mark S. Schubert, MD

12:30-1:50

LUNCH
Grande Promenade 

Selected Talks from Junior Investigators
1:50-1:55 Session Introduction
Moderators: William J. Steinbach, MD and Karl V. Clemons, PhD
1:55-2:05

The role of sialic acids on the surface of Aspergillus fumigatus and the characterization of an a. Fumigatus sialidase
Mark Warwas

2:05-2:15

The timing of myeloid cell depletion relative to infection determines the outcome of invasive Aspergillosis
Monica Mircescu

2:15-2:25

Human platelets influence cell wall assembly in Aspergillus fumigatus
Susanne perkhofer

Aspergillus Species / Strain Differences
2:25-2:30 Session Introduction
Moderators: Scott E. Baker, PhD and Katsu Kamei, MD, PhD
2:30-2:55 Criteria for Aspergillus speciation: Utrecht meeting summary
Robert A. Samson, PhD
2:55-3:20 MLST vs. Microsatellites
Corne Klaasen, PhD
3:20-3:45 Comparison of the two sequenced A. fumigatus strains
Natalie D. Federova, PhD
3:45-4:10 A. terreus complex
S. Arun Balajee, PhD

4:10-4:35

BREAK
Grande Promenade 

Vaccine and T Cell Immunity
4:35-4:40 Session Introduction
Moderators: Luigina Romani, MD, PhD and Jill Adler-Moore, MD
4:40-5:05 Cultivated TH1 cells
Thomas Lehrnbecher, MD, PhD
5:05-5:30 Host response signatures to invasive aspergillosis
Teresa Zelante, PhD
5:30-5:55 Vaccine progress
James I. Ito, MD
6:00-7:20

POSTER SESSION #1 with drinks/snacks

Session 1 - Posters 1-36
Castillian, Valencia Madrid Rooms. Mezzanine Level.

Session 2 - Posters 37-97
Grande Promenade. Main Lobby Level.

Satellite Symposia
Risk Stratification for Invasive Aspergillosis and Prophylaxis
Starlight Ballroom (Top of Resort)
7:30-9:30 Risk stratification for invasive aspergillosis: Early assessment of host
susceptibility

Thomas F. Patterson, MD

Prophylaxis limitations: Challenges in the management of invasive Aspergillosis
Pranatharthi H. Chandrasekar, MD

Interactive case studies: Improving clinical outcomes in invasive
Aspergillosis

Nina Singh, MD

Friday, January 18 [back to top of page]

7:30-8:45

BREAKFAST
Grande Promenade 

8:00-8:45 Meet the Professors (parallel sessions)

Recognizing therapeutic failure - case illustrations and challenges
Kent Sepkowitz, MD
Mediterranean East and Center

Inflammation in Aspergillus immunology
Luigina Romani, MD, PhD
Regency Ballroom

Alternative Imaging in Invasive Aspergillosis
Mediterranean East and Center
8:55-9:00 Session Introduction
Moderators: Dimitrios P. Kontoyiannis, MD and Jose G. Montoya, MD
9:00-9:25 Galactomannan and beyond:  MRI and PET for diagnosis
Elias Anaissie, MD
9:25-9:50 Functionalized nanocarriers to image and target fungi infected immune cells
Suresh P. Vyas, PhD
9:50-10:15 Live-cell imaging of Aspergillus in vitro
Nick Read, PhD
10:15-10:40 Imaging in animals with invasive aspergillosis
Thomas J. Walsh, MD

10:40-11:05

BREAK
Grande Promenade 

Controlling Aspergillus in buildings
11:05-11:10 Session Introduction
Moderators: Thomas M. Chiller, MD and Elias J. Anaissie, MD
11:10-11:35 Infection control and HICPAC guidelines
David J. Weber, MD, MPH
11:35-12:00 Nosocomial asperigllosis:  review and building construction cases
Donna Haiduven, PhD
12:00-12:30 Sick building debate: Is mould the cause?
Abba I. Terr, MD

1:00-6:00

LUNCH and CHOICE OF THREE TOURS
Board Busses in Front of Hotel

6:00-7:30

POSTER SESSION #2 with drinks/snacks

Session 1 - Posters 1-36
Castillian, Valencia Madrid Rooms. Mezzanine Level.

Session 2 - Posters 37-97
Grande Promenade. Main Lobby Level.

Satellite Symposia
Invasive Fungal Infections in Patients With Hematologic Malignancies: Will New Strategies For Treatment Lead to New Opportunities for Improving Patient Outcome?
Starlight Ballroom – Top of Resort
7:30-9:30 Amphotericin B: Past, present and future
Michael Kleinberg, MD PhD

Newer antifungal delivery systems
Richard H. Drew, PharmD

Cerebral aspergillosis: Tissue penetrance is the key
Stefan Schwartz, MD


Saturday, January 19 [back to top of page]

7:30-8:45

BREAKFAST
Grande Promenade 

8:45-8:55 Awards and Scholarships Presentation
David A. Stevens, MD
Mediterranean East and Center
Aspergillus and Asthma / ABPA
Cystic Fibrosis Foundation Symposia
8:55-9:00 Session Introduction
Moderators: Richard B. Moss, MD and David W. Denning, MD
9:00-9:25 Phenotypes of severe asthma
Sally E. Wenzel, MD
9:25-9:50 Differences in the immunobiology of Aspergillus colonization and ABPA?
Jay K. Kolls, MD
9:50-10:15 Regulation of immunity in bronchiectasis and ABPA
Rosemary Boyton, MD
10:15-10:40 Mechanisms behind the cystic fibrosis - ABPA link
Dominik Hartl, MD

10:40-11:05

BREAK
Grande Promenade 

Secondary Metabolites from Aspergillus
11:05-11:10 Session Introduction
Moderators: Joan Bennett, PhD and June Kwon-Chung, PhD
11:10-11:35 Genomic insights about secondary metabolite gene clusters/pathways
William C. Nierman, PhD
11:35-12:00 Aspergillus metabolites in vivo
Robert A. Cramer, Jr., PhD
12:00-12:25 Aspergillus and biotechnology
Scott Baker, PhD
12:25-12:50 Metabolomics of A. fumigatus
Jens Frisvad, PhD

12:50-2:15

LUNCH
Grande Promenade 

Aspergillus growth towards pathogenicity
2:15-2:20 Session Introduction
Moderators: Reinhard Fischer, PhD and Nir Osherov, PhD
2:20-2:45 Interaction of Aspergillus with human bronchial mucosa
Ryoichi Amitani, PhD
2:45-3:10 Lung epithelial cell invasion
William W. Hope, MD, PhD
3:10-3:35 Biofilm formation by Aspergillus
Gordon Ramage, PhD
3:35-4:00 Differences in pathogenicity and clinical syndromes due to A. fumigatus and A. flavus
Alessandro C. Pasquallotto, MD PhD
4:00-4:05 Conference Farewell
David W. Denning, MD
5:00- 5:45 Planning for AAA 2010 Conference
Open planning session (everyone invited) to discuss ideas and plans for next meeting in 2010